BUILD YOUR OWN GENE MUTATION!

We've been learning about the different mutations that occur within genes and chromosomes. As an engineering practice, your goal for today is to work with your group to do the following:

I can develop and use a model to describe why changes to genes (mutations) may result in harmful, neutral, or beneficial effects to the structure a d function of an organism.

Label this activity "Gene Mutation Engineering" on a new page in your journal.

With your group partners, first build a model of DNA using the pop beads with the following codon sequence:

ATG-CTC

**You must make a key in your journal to show the color of each nucleotide base**

1) Once you have finished your model, raise your hand as a group and I will come around and take a picture of your model. 2) Next, create a mutation in your model to show the change within a gene. I will assign you the specific mutation your are to demonstrate. Each student must use arrows in labeling in your journal to demonstrate the change. 3) Raise your hand as a group again and I will check the construction of your mutation. If correct, I will take an "after" photo so we can compare the differences on our website.

Extend: Draw an example of the same mutation in DNA, but this time show it in a chromosome.

ATG-CTC